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Index > Protein center > TLR9(Gene name) > Dog
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  • TLR9 (Gene name),
  • Toll-like receptor 9 (Protein name ),  TLR9_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TLR9;
    Protein name:
    Toll-like receptor 9;
    Alternative:

    CD:
    CD289;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with BTK and CNPY3 (By similarity). Interacts (via transmembrane domain) with UNC93B1.
    Function:
    Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
    Subcellular Location:
    Endoplasmic reticulum membrane Single-pass type I membrane protein Endosome Lysosome Cytoplasmic vesicle phagosome Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
    Protein Attributes:
    Sequence length:
    1032
    Sequence:
    50:
    MGPCRGALHP | LSLLVQAAAL | ALALAQGTLP | AFLPCELQPH | GLVNCNWLFL | 
    100:
    KSVPRFSAAA | PRGNVTSLSL | YSNRIHHLHD | YDFVHFVHLR | RLNLKWNCPP | 
    150:
    ASLSPMHFPC | HMTIEPNTFL | AVPTLEDLNL | SYNSITTVPA | LPSSLVSLSL | 
    200:
    SRTNILVLDP | ATLAGLYALR | FLFLDGNCYY | KNPCQQALQV | APGALLGLGN | 
    250:
    LTHLSLKYNN | LTVVPRGLPP | SLEYLLLSYN | HIITLAPEDL | ANLTALRVLD | 
    300:
    VGGNCRRCDH | ARNPCRECPK | GFPQLHPNTF | GHLSHLEGLV | LRDSSLYSLD | 
    350:
    PRWFHGLGNL | MVLDLSENFL | YDCITKTKAF | YGLARLRRLN | LSFNYHKKVS | 
    400:
    FAHLHLASSF | GSLLSLQELD | IHGIFFRSLS | KTTLQSLAHL | PMLQRLHLQL | 
    450:
    NFISQAQLSI | FGAFPGLRYV | DLSDNRISGA | AEPAAATGEV | EADCGERVWP | 
    500:
    QSRDLALGPL | GTPGSEAFMP | SCRTLNFTLD | LSRNNLVTVQ | PEMFVRLARL | 
    550:
    QCLGLSHNSI | SQAVNGSQFV | PLSNLRVLDL | SHNKLDLYHG | RSFTELPRLE | 
    600:
    ALDLSYNSQP | FSMRGVGHNL | SFVAQLPALR | YLSLAHNGIH | SRVSQQLRSA | 
    650:
    SLRALDFSGN | TLSQMWAEGD | LYLRFFQGLR | SLVQLDLSQN | RLHTLLPRNL | 
    700:
    DNLPKSLRLL | RLRDNYLAFF | NWSSLALLPK | LEALDLAGNQ | LKALSNGSLP | 
    750:
    NGTQLQRLDL | SGNSIGFVVP | SFFALAVRLR | ELNLSANALK | TVEPSWFGSL | 
    800:
    AGALKVLDVT | ANPLHCACGA | TFVDFLLEVQ | AAVPGLPSRV | KCGSPGQLQG | 
    850:
    RSIFAQDLRL | CLDEALSWVC | FSLSLLAVAL | SLAVPMLHQL | CGWDLWYCFH | 
    900:
    LCLAWLPRRG | RRRGVDALAY | DAFVVFDKAQ | SSVADWVYNE | LRVQLEERRG | 
    950:
    RRALRLCLEE | RDWVPGKTLF | ENLWASVYSS | RKTLFVLART | DRVSGLLRAS | 
    1000:
    FLLAQQRLLE | DRKDVVVLVI | LCPDAHRSRY | VRLRQRLCRQ | SVLLWPHQPS | 
    1032:
    GQRSFWAQLG | TALTRDNRHF | YNQNFCRGPT | TA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Toll-like receptor 9
    Cat.:
    E0709h
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    96T
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    ELISA Kit for Dog Toll-like receptor 9
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    E0709p
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    ELISA Kit for Dog Toll-like receptor 9
    Cat.:
    E0709d
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    Packing:
    96T
    ELISA Kit for Dog Toll-like receptor 9
    Cat.:
    E0709m
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    96T
    ELISA Kit for Dog Toll-like receptor 9
    Cat.:
    E0709b
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    Packing:
    96T
    CLIA Kit for Dog Toll-like receptor 9
    Cat.:
    U0709p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Toll-like receptor 9
    Cat.:
    U0709h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Toll-like receptor 9
    Cat.:
    U0709b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Toll-like receptor 9
    Cat.:
    U0709d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Toll-like receptor 9
    Cat.:
    U0709m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Dog Toll-like receptor 9
    Polyclonal Antibody for Dog Toll-like receptor 9
    Cat.:
    P0709Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Toll-like receptor 9
    Polyclonal Antibody for Dog Toll-like receptor 9
    Cat.:
    P0709Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Toll-like receptor 9
    Monoclonal Antibody for Dog Toll-like receptor 9
    Monoclonal Antibody for Dog Toll-like receptor 9
    Monoclonal Antibody for Dog Toll-like receptor 9
    Monoclonal Antibody for Dog Toll-like receptor 9
    Monoclonal Antibody for Dog Toll-like receptor 9
    Protein for Dog Toll-like receptor 9
    Protein for Dog Toll-like receptor 9
    Protein for Dog Toll-like receptor 9
    Protein for Dog Toll-like receptor 9
    Protein for Dog Toll-like receptor 9

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    References
    1. 1.
      "Canis familiaris toll-like receptor 9 mRNA."
      Brownlie R. , Mookherjee N. , Mutwiri G. , Babiuk L. , Hecker R. , Lipford G. , Griebel P.
      Submitted (2004-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Spleen.
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